“- Walter Fielding: Has this ever happened to you before?
- Jack Schnittman: Yes.
- Paramedic: Seven times in the past five months.
- Walter Fielding: I thought the jogging was getting you in better shape.
- Jack Schnittman: It is.
- Paramedic: Yeah thanks to the jogging I can lift him into the ambulance.”

Tom Hanks - Walter Fielding
Josh Mostel - Jack Schnittman
Wendell Pierce - Paramedic

“Keep cooking like that and I won't even be able to move, let alone do science.”

Larry Blamire - Dr. Paul Armstrong

“- Lara: You really think I'm skinny? Bulimic skinny or anorexic skinny?
- Lauren Hynde: What's the difference?
- Lara: Bulimic skinny passes for healthy, except your teeth rot. But my teeth aren't rotting, so...”
Shannyn Sossamon - Lauren Hynde
Jessica Biel - Lara

“- Lara: It's amazing how much weight you lose when you go off The Pill.
- Lauren Hynde: Which is nothing compared to the fifty pounds you gain when you get knocked up.”
Jessica Biel - Lara
Shannyn Sossamon - Lauren Hynde

“You want your sister to lose weight? Tell her to get off the couch, stop eating Twinkies and maybe go out for field hockey. You know what? No one ever knows what they want to be when they grow up. You know, it takes a little, little while to find that out.”

Jake Gyllenhaal - Donnie Darko