“- Lady Eboshi: Stay here. Help me kill the Forest Spirit, Ashitaka.
- Ashitaka: You would do that? Kill the very heart of the forest?
- Lady Eboshi: Without that ancient god, the animals here would be nothing but dumb beasts once again.”
Minnie Driver - Lady Eboshi
Billy Crudup - Ashitaka

“- Sherman: Do I look like an animal shelter?
- Natty Gann: Don't worry, I'll keep this one.
- Sherman: That's what you said the last time.”

Scatman Crothers - Sherman
Meredith Salenger - Natty Gann

“- Emma: Put the baby squirrel back in the tree.
- Jake: What baby squirrel?
[Emma looks at her watch then holds out her hand to catch the falling baby squirrel]
- Jake: That happens every day?
- Emma: Like clockwork.”
Ella Purnell - Emma
Asa Butterfield - Jake

“It's a bug-eat-bug world out there, princess. One of those Circle of Life kind of things. Now let me tell you how things are supposed to work: The sun grows the food, the ants pick the food, the grasshoppers eat the food...”
Kevin Spacey - Hopper

“- Delmar O'Donnell: This stew's awful good.
- Wash Hogwallop: [examining his fork] You think so? I slaughtered this horse last Tuesday... I'm afraid she's startin' to turn.”
Tim Blake Nelson - Delmar O'Donnell
Frank Collison - Wash Hogwallop