“- Samantha Harper: You're down in New York consulting with Lou Gerstner or the head of GE telling them how to buy South American countries but on the weekends, you fly back up here to hang out with the cop, do cop things, maybe go to cop mixers...
- Katie Burke: I like the cop.
- Samantha Harper: Yeah, um, I can see that.”
Zooey Deschanel - Samantha Harper
Katie Holmes - Katie Burke

“I like London. You know I did my research before I came. I came because I found out it was my kind of town. I mean the cops don't carry guns. Now the cops still try and chase the bad guys; but they don't find it necessary to kill him when they catch him. I call that civilized. That's one of the reasons I left New York to come here.”
Ed Lauter - Smoke

“- Kate McCallister: What kind of idiots do you have working here?
- Desk Clerk: The finest in New York.”
Catherine O'Hara - Kate McCallister
Dana Ivey - Desk Clerk

“You know, I have met some dumb blondes in my life, but you take the taco, pal! Only a Carpathian would come back to life now and choose New York! Tasty pick, bonehead! If you had brain one in that huge melon on top of your neck, you would be living the sweet life out in Southern California's beautiful San Fernando Valley!”

Bill Murray - Dr. Peter Venkman

“I know we're Valley detectives so we're not all that bright, but how stupid does he think we are?”

Keith Carradine - Detective Creighton