“- Connie Conehead: I think I'll have some Tang.
- Prymatt Conehead: Ah Tang, the drink astronauts took to the moon.
- Beldar Conehead: Astronauts to the moon?”
Michelle Burke - Connie Conehead
Jane Curtin - Prymatt Conehead
Dan Aykroyd - Beldar Conehead

“I'm not an astronaut. I'm an engineer. What am I'm doing here?”
John Lithgow - Dr. Walter Curnow

“- Vincent: A year is a long time.
- Irene: Not so long. Just once around the sun.”
Ethan Hawke - Vincent Freeman
Uma Thurman - Irene Cassini

“- Jack: There's only two times when that kind of thing's okay: in prison where it's a substitute and guys in space.
- Mike: Guys in space?
- Jack: Well, not on purpose. They just float into each other.”

Shawn Hatosy - Jack
Zak Orth - Mike

“I am very pleased with the results of the astronomy test. Although, there's still some confusion about Pluto. While its planetary classification is still uncertain, it is definitely not Mickey's dog.”
Grace Phillips - Miss Landers