“- Max Wesley: Why do you care, anyway?
- Jesse: If one of your friends was in trouble, wouldn't you try to help him?
- Max Wesley: If I could.
- Jesse: My friends are whales.”
Vincent Berry - Max Wesley
Jason James Richter - Jesse

“- Hilary O'Neil: What is it?
- Victor Geddes: Raw cow... dead.
- Hilary O'Neil: What if I throw up?
- Victor Geddes: Then I'll take care of you.”
Julia Roberts - Hilary O'Neil
Campbell Scott - Victor Geddes

“It looks safe. Come on. Come on! It's empty! Nothin' in here but a pig, and he sure don't care.”

John Cusack - Harry

“- Dr. Wallace Wrightwood: So what you're saying is you would be willing, excuse me, Jack would be willing to take in this creature and care for it and love it like a pet?
- George Henderson: No, like a member of the family.”

Don Ameche - Dr. Wallace Wrightwood
John Lithgow - George Henderson

“We're goldfish people, we're antfarm people. We're not dog people.”

Charles Grodin - George Newton