“- Mitch: I don't mean to be rude, but aren't you a little old to be starting medical school?
- Patch Adams: You know, Babe Ruth was 39 when he joined the Yankees.
- Mitch: No, he wasn't!
- Patch Adams: I know. If you have a better example, please tell me.”
Philip Seymour Hoffman - Mitch
Robin Williams - Patch Adams

“My doctor totally messes up my nose job. I ask him to make me looked like Gwyneth Paltrow, I get off the surgery table looking life freakin' Shrek.”
Shawn Wayans - Kevin Copeland

- Dr. Kersten: Funky, buttloving!
- George: Did he say "funky buttloving?"
Ross Lehman - Dr. Kersten
Patrick LaBrecque - George

“- Eugene G. Roe: You're a good nurse.
- Renee Lemaire: No. I never want to treat another wounded man again. I'd rather work in a butcher's shop.”
Shane Taylor - Eugene G. Roe
Lucie Jeanne - Renee Lemaire

“I'm a doctor, not a space explorer.”
Heather Graham - Dr. Judy Robinson