- Spencer Tracy: Trouble with Mr. Hughes?
- Katharine Hepburn: There's too much "Howard Hughes" in Howard Hughes. That's the trouble.
Kevin O'Rourke - Spencer Tracy
Cate Blanchett - Katharine Hepburn

“You think it's healthy to obsessively collect things? You can't connect with other people, so you fill your life with stuff. I'm just like all the rest of these pathetic collector losers.”

Steve Buscemi - Seymour

“I am loved and respected by all who know me - slightly.”
Johnny Depp - Mortdecai

“Life sucks because my wife left me for an off broadway monologuist.”
Jemaine Clement - Will Henry

“- Edie: I've never met anyone like you. There's not a spark of sentiment or romance or human kindness in your whole body.
- Terry: What good does it do you but get you in trouble?”
Eva Marie Saint - Edie Doyle
Marlon Brando - Terry Malloy