“It kill your brain cells, son. It kill your brain cells! Now when you're destroying your brain cells, your doing the same thing as killing yourself. You just doing it slower! Now, I say, if wanna kill yourself, don't fuck around with it. Go on and do it expeditiously!”

Morgan Freeman - Principal Joe Clark

“- Mysterious Woman: This is your brain.
- Toddster: Dude, my brain!
- Mysterious Woman: And this is your brain on drugs!”

Sheri Wenden - Mysterious Woman
Gary Hrbek - Toddster

“I accumulated quite a healthy complex, not to mention a complexion. Then one day I discovered the most ultimate form of expression ever: marijuana. Oh, boy... pot! I could escape all day long and not have routine nervous breakdowns.”
Kurt Cobain - Himself

“A bit of morning cocaine always helps the brain.”
John C. Reilly - Dr. Watson

“Caesar shows cognitive skills that far exceed that of a human counterpart. The drug in his system has radicly boosted healthy brain functions.”
James Franco - Will Rodman