“- Francis Buxton: Today's my birthday and my father says I can have anything I want.
- Pee-wee Herman: Good for you and your father.
- Francis Buxton: So guess what I want.
- Pee-wee Herman: A new brain.”
Mark Holton - Francis Buxton
Paul Reubens - Pee-wee Herman

“- Timon: What do you call a hyena with half a brain?
- Pumbaa: Beats me, Timon. What?
- Timon: Gifted!”
Nathan Lane - Timon
Ernie Sabella - Pumbaa

“To have a brain, it's not a sin. To have a brain and not use it, that is a sin.”
Armin Mueller-Stahl - Doc

“You're going to have to use your brain which is going to hurt because it's the weakest muscle in your body.”
Paul Hogan - Porter Ricks

“You've a magnificent brain, Moriarty. I admire it. I admire it so much I'd like to present it pickled in alcohol to the London Medical Society.”
Basil Rathbone - Sherlock Holmes