“I am going into that room to my boy. You may shoot if you want to.”

Josephine Crowell - Mrs. Cameron

“We're his parents, we'll handle this. Diane, how do we handle this?”

Rick Moranis - Wayne

“- Ellen Griswold: Gee Cath looks like you really got your hands full.
- Cousin Catherine: Oh, it's not so bad. Eddie says after the baby comes, I can quit one of my night jobs.”
Beverly D'Angelo - Ellen Griswold
Miriam Flynn - Cousin Catherine

“You're mother earth incarnate.”
Julia Roberts - Isabel Kelly

“- Ben Harrison: No one loves you like I do.
- Jackie Harrison: No. No one ever will.”
Liam Aiken - Ben Harrison
Susan Sarandon - Jackie Harrison