“- Hal: What are you doing?
- Mauricio: I am rescuing you.
- Hal: From what?
- Mauricio: From what? From a pack of stampeding buffalo, that's what!”

Jack Black - Hal
Jason Alexander - Mauricio

“- Bobo: You're the one who's fat!
- L'il Debbull: Not as fat as you!”
Dan Aykroyd - Bobo
John Daveikis - L'il Debbull

“- Wilbur Turnblad: This is America, babe, you gotta think big to be big.
- Edna Turnblad: Big ain't the problem in this family, Wilbur.”

Christopher Walken - Wilbur Turnblad
John Travolta - Edna Turnblad

“Big fat guy, I mean like orca fat.”

Kevin Spacey - Verbal

“- Dutch Dooley: Doyle, switch cots with me, mine won't hold me.
- Doyle Standish : How do you know it'll hold me?
- Dutch Dooley: Because I'm 15,000 cheeseburgers ahead of you in life.”
Ed O'Neill - Dutch Dooley
Ethan Embry - Doyle Standish