“- Drix: Where did you study?
- Osmosis Jones: Study? When you grow up on the wrong side of the digestive track, you ain't got no money for no fancy schools.”
David Hyde Pierce - Drix
Chris Rock - Osmosis Jones

“- Myrna Goldfarb: I happen to have a Master's degree in African-American studies.
- Pierre Delacroix: So you fucked a nigger in college.”
Dina Pearlman - Myrna Goldfarb
Damon Wayans - Pierre Delacroix

“Some of you may have had easy lives up until now. Some of you may not. Life this semester won't be easy for any of you. Your grades in your first year of law school can determine your entire future in the law.”
James Earl Jones - Professor Banks

“- Sylvie Cooper: So what are you busted for?
- Ivy: I gotta keep a certain grade point average. I'm slipping in biology.”
Sara Gilbert - Sylvie Cooper
Drew Barrymore - Ivy

“I'm an engineer! I stopped running when Nixon was president!”
Donald Sutherland - Jerry O'Neill