“- James Griswold: I've never even heard of the original vacation.
- Rusty Griswold: Doesn't matter. The new vacation will stand on its own.”
Skyler Gisondo - James Griswold
Ed Helms - Rusty Griswold

“- Inspector Arthur Steed: And there's nothing left but to stop you.
- Maud Watts: What are you gonna do? Lock us all up? We're in every home, we're half the human race, you can't stop us all.”

Brendan Gleeson - Inspector Arthur Steed
Carey Mulligan - Maud Watts

“Welly, welly, welly, welly, welly, welly, well. To what do I owe the extreme pleasure of this surprising visit?”
Malcom McDowell - Alex (A Clockwork Orange)

“Enjoying that are you my darlin'? Bit cold and pointless isn't it my lovely? What's happened to yours, my little sister?”

Malcom McDowell - Alex (A Clockwork Orange)

“- Merrill Hess: Excluding the possibility that a female Scandinavian Olympian was running around outside our house last night, what else might be a possibility?
- Officer Paski: I'm not done asking questions. And I don't appreciate sarcasm.”
Joaquin Phoenix - Merrill Hess
Cherry Jones - Officer Paski