“- Montgomery: Well, things didn't work out. Moreau wanted to turn animals into humans and humans into gods. But it's instinct and reason, instinct and reason. What's reason to a dog?
- Azazello: To hunt. To kill, master. To run with the pack.
- Montgomery: I wanna go to Dog Heaven!”
Val Kilmer - Montgomery
Temuera Morrison - Azazello

“- Kimble: This is your new class mascot.
- Boy: What happened to your dog?
- Kimble: This is not a dog. This is a ferret.”

Arnold Schwarzenegger - Kimble

“- Gordie: Mickey's a mouse, Donald's a duck, Pluto's a dog. What's Goofy?
- Teddy: Goofy's a dog. He's definitely a dog.
- Chris: He can't be a dog. He drives a car and wears a hat.
- Vern: Oh, God. That's weird. What the hell is Goofy?”
Wil Wheaton - Gordie Lachance
Corey Feldman - Teddy Duchamp
River Phoenix - Chris Chambers
Jerry O'Connell - Vern Tessio

“Hello, dog. What do you want, eh? You like my feet, do you? Have your fill and away you go. Feet are considered a delicacy among certain animals, you know.”
Peter Sellers - Hrundi V. Bakshi

“- Billy Bob: I sure do love that dog.
- Mox: I think it's a pig.
- Billy Bob: Yeah.”
Ron Lester - Billy Bob
James Van Der Beek - Mox