“- Justin: So is Max like a bad dog?
- Reyes: Max is as good a dog as ever passed through this facility. Animals can come down with post-traumatic stress just the same as people.”
Josh Wiggins - Justin Wincott
Jay Hernandez - Sergeant Reyes

“- Montgomery: Well, things didn't work out. Moreau wanted to turn animals into humans and humans into gods. But it's instinct and reason, instinct and reason. What's reason to a dog?
- Azazello: To hunt. To kill, master. To run with the pack.
- Montgomery: I wanna go to Dog Heaven!”
Val Kilmer - Montgomery
Temuera Morrison - Azazello

“I know something about this dog. She's going somewhere - she's on her way.”
May Whitty - Dally

“- Mrs. Carraclough: Lassie won't be waiting for you at school anymore.
- Joe Carraclough: Why not? What's happened?
- Mrs. Carraclough: Because she's sold; that's why not.”
Elsa Lanchester - Mrs. Carraclough
Roddy McDowall - Joe Carraclough

“You're my Lassie come home.”
Roddy McDowall - Joe Carraclough