“- Holloway: You've got a gift.
- Leaven: It's not a gift. It's just a brain.”

Nicky Guadagni - Holloway
Nicole de Boer - Leaven

“- Francis Buxton: Today's my birthday and my father says I can have anything I want.
- Pee-wee Herman: Good for you and your father.
- Francis Buxton: So guess what I want.
- Pee-wee Herman: A new brain.”
Mark Holton - Francis Buxton
Paul Reubens - Pee-wee Herman

“Caesar shows cognitive skills that far exceed that of a human counterpart. The drug in his system has radicly boosted healthy brain functions.”
James Franco - Will Rodman

“- Ross Jennings: Chris, I'm scared to death.
- Chris Collins: Yeah, we all are, but our brains secrete a neurotransmitter that enables us to deal with them.
- Ross Jennings: I don't think I have that particular neurotransmitter.”
Jeff Daniels - Ross Jennings
Brian McNamara - Chris Collins

“- Ursula Stanhope: Did you fight a crocodile for this?
- George: Oh, no. George not fight. Crocodile have toothache. George pull tooth. Crocodile give to George after. Gift.”

Leslie Mann - Ursula Stanhope
Brendan Fraser - George