“- Dr. John Dolittle: I didn't say you were crazy, you're special, and crazy, a lot of great people in history were crazy.
- Maya Dolittle: Like who?
- Dr. John Dolittle: Some of the greatest people in history.”
Eddie Murphy - Dr. John Dolittle
Kyla Pratt - Maya Dolittle

“All of us are freaks in one way or another.”
Sir John Hurt - The Countess

“- Mitch: Kenny has to go. He's cooking breakfast for his underwear.
- Dr. Jeffrey Sanborn: Who is this?
- Mitch: I'm a pair of his socks.”

Billy Crystal - Mitch Robbins
Bob Balaban - Dr. Jeffrey Sanborn

“- Putnam: All right, I'm looking for a couple of kids. This one's a mental case, have you seen them?
- Pinball Teen: Does he dress like you?
- Putnam: No.
- Pinball Teen: Then he can't be too much of a case, all right?”
Will Seltzer - Putnam
Tom Kerley - Pinball Teen

“You're plenty original without having to order something weird to drink.”
Kate Beckinsale - Charlotte