“- Lauren Hannon: You know, you're a better sister to me than my own sister.
- Melissa: Yeah, and Dick Cheney is a better sister to you than your sister.”

Crystal Lowe - Lauren Hannon
Michelle Trachtenberg - Melissa

“- Evelyn Carnahan: You lied to me.
- Jonathan Carnahan: I lie to everybody. What makes you so special?
- Evelyn Carnahan: I am your sister.
- Jonathan Carnahan: Yes, well, that just makes you more gullible.”
Rachel Weisz - Evelyn Carnahan
John Hannah - Jonathan Carnahan

“- Bessie: I wish we could get along.
- Lee: We do get along.
- Bessie: No I know, but I mean really get along and be polite with one another.
- Lee: We're sisters.”
Diane Keaton - Bessie
Meryl Streep - Lee

“My sister, who swiped every guy I ever had my eye on, has now swiped the last guy in the whole freaked out world!”
Kelli Maroney - Samantha Belmont

“- Granny: Your only sister, all alone in the wood, and nobody there to save her. Poor little lamb.
- Rosaleen: Why couldn't she save herself?
- Granny: You don't know anything, you're only a child.”
Dame Angela Lansbury - Granny
Sarah Patterson - Rosaleen